Research Initiatives

Our research lies at the intersection of microbial ecology, computational biology, and human health. We are interested in the role host-microbe interactions play in shaping the emergence, persistence, and progression of cardiometabolic disease and health outcomes.

Our Research

We leverage athletes as a model system because they ideally represent how sustained physiological stress, diet, and recovery shape the gut-host axis, uncovering insights in:

  • Physiological perturbations

  • Metabolic flexibility

  • Diet-microbe interactions

  • Multi-modal phenotyping

  • Recovery, adaptations, and overtraining

  • Population health

Model System

We integrate multi-omics, machine learning, and experimental validation to move from discovery to causation via (I) data-driven translation, (II) characterization of microbial pathways that link to host phenotypes, and (III) employ in vitro and in vivo interventions that validate mechanistic hypotheses.

Our Approach